Baseline Microglial Activation Correlates With Brain Amyloidosis and Longitudinal Cognitive Decline in Alzheimer Disease

BACKGROUND AND OBJECTIVES: This study aims to quantify microglial activation in individuals with Alzheimer disease (AD) using the 18-kDa translocator protein (TSPO) PET imaging in the hippocampus and precuneus, the 2 AD-vulnerable regions, and to evaluate the association of baseline neuroinflammatio...

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Detalles Bibliográficos
Autores principales: Wang, Qing, Chen, Gengsheng, Schindler, Suzanne E., Christensen, Jon, McKay, Nicole S., Liu, Jingxia, Wang, Sicheng, Sun, Zhexian, Hassenstab, Jason, Su, Yi, Flores, Shaney, Hornbeck, Russ, Cash, Lisa, Cruchaga, Carlos, Fagan, Anne M., Tu, Zhude, Morris, John C., Mintun, Mark A., Wang, Yong, Benzinger, Tammie L.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906187/
https://www.ncbi.nlm.nih.gov/pubmed/35260470
http://dx.doi.org/10.1212/NXI.0000000000001152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906187/
https://www.ncbi.nlm.nih.gov/pubmed/35260470
http://dx.doi.org/10.1212/NXI.0000000000001152

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