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Hippocampal neurons maintain a large PtdIns(4)P pool that results in faster PtdIns(4,5)P(2) synthesis

PtdIns(4,5)P(2) is a signaling lipid central to the regulation of multiple cellular functions. It remains unknown how PtdIns(4,5)P(2) fulfills various functions in different cell types, such as regulating neuronal excitability, synaptic release, and astrocytic function. Here, we compared the dynamic...

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Detalles Bibliográficos
Autores principales: de la Cruz, Lizbeth, Kushmerick, Christopher, Sullivan, Jane M., Kruse, Martin, Vivas, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906353/
https://www.ncbi.nlm.nih.gov/pubmed/35179558
http://dx.doi.org/10.1085/jgp.202113001