Tyrosine phosphatase SHP2 exacerbates psoriasis‐like skin inflammation in mice via ERK5‐dependent NETosis

Psoriasis is a chronic inflammatory skin disease, often accompanied by increased infiltration of immune cells, especially neutrophils. However, the detailed mechanism of the neutrophil function in psoriasis progression remains unclear. Here, we found that both Src homology‐2 domain‐containing protei...

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Detalles Bibliográficos
Autores principales: Ding, Yan, Ouyang, Zijun, Zhang, Chenyang, Zhu, Yuyu, Xu, Qiang, Sun, Haiyan, Qu, Jiao, Sun, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906448/
https://www.ncbi.nlm.nih.gov/pubmed/35281792
http://dx.doi.org/10.1002/mco2.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906448/
https://www.ncbi.nlm.nih.gov/pubmed/35281792
http://dx.doi.org/10.1002/mco2.120

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