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Three-Dimensional Model of Sub-Plasmalemmal Ca(2+) Microdomains Evoked by T Cell Receptor/CD3 Complex Stimulation

Ca(2+) signalling plays an essential role in T cell activation, which is a key step to start an adaptive immune response. During the transition from a quiescent to a fully activated state, Ca(2+) microdomains of reduced spatial and temporal extents develop in the junctions between the plasma membran...

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Detalles Bibliográficos
Autores principales: Gil, Diana, Diercks, Björn-Philipp, Guse, Andreas H., Dupont, Geneviève
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906516/
https://www.ncbi.nlm.nih.gov/pubmed/35281279
http://dx.doi.org/10.3389/fmolb.2022.811145