Three critical regions of the erythromycin resistance methyltransferase, ErmE, are required for function supporting a model for the interaction of Erm family enzymes with substrate rRNA

6-Methyladenosine modification of DNA and RNA is widespread throughout the three domains of life and often accomplished by a Rossmann-fold methyltransferase domain which contains conserved sequence elements directing S-adenosylmethionine cofactor binding and placement of the target adenosine residue...

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Detalles Bibliográficos
Autores principales: Sharkey, Rory E., Herbert, Johnny B., McGaha, Danielle A., Nguyen, Vy, Schoeffler, Allyn J., Dunkle, Jack A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906542/
https://www.ncbi.nlm.nih.gov/pubmed/34795028
http://dx.doi.org/10.1261/rna.078946.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906542/
https://www.ncbi.nlm.nih.gov/pubmed/34795028
http://dx.doi.org/10.1261/rna.078946.121

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