Identification of high-confidence human poly(A) RNA isoform scaffolds using nanopore sequencing

Nanopore sequencing devices read individual RNA strands directly. This facilitates identification of exon linkages and nucleotide modifications; however, using conventional direct RNA nanopore sequencing, the 5′ and 3′ ends of poly(A) RNA cannot be identified unambiguously. This is due in part to RN...

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Detalles Bibliográficos
Autores principales: Mulroney, Logan, Wulf, Madalee G., Schildkraut, Ira, Tzertzinis, George, Buswell, John, Jain, Miten, Olsen, Hugh, Diekhans, Mark, Corrêa, Ivan R., Akeson, Mark, Ettwiller, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906549/
https://www.ncbi.nlm.nih.gov/pubmed/34728536
http://dx.doi.org/10.1261/rna.078703.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906549/
https://www.ncbi.nlm.nih.gov/pubmed/34728536
http://dx.doi.org/10.1261/rna.078703.121

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