Cargando…

Identification of high-confidence human poly(A) RNA isoform scaffolds using nanopore sequencing

Nanopore sequencing devices read individual RNA strands directly. This facilitates identification of exon linkages and nucleotide modifications; however, using conventional direct RNA nanopore sequencing, the 5′ and 3′ ends of poly(A) RNA cannot be identified unambiguously. This is due in part to RN...

Descripción completa

Detalles Bibliográficos
Autores principales: Mulroney, Logan, Wulf, Madalee G., Schildkraut, Ira, Tzertzinis, George, Buswell, John, Jain, Miten, Olsen, Hugh, Diekhans, Mark, Corrêa, Ivan R., Akeson, Mark, Ettwiller, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906549/
https://www.ncbi.nlm.nih.gov/pubmed/34728536
http://dx.doi.org/10.1261/rna.078703.121

Ejemplares similares