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Identification of high-confidence human poly(A) RNA isoform scaffolds using nanopore sequencing
Nanopore sequencing devices read individual RNA strands directly. This facilitates identification of exon linkages and nucleotide modifications; however, using conventional direct RNA nanopore sequencing, the 5′ and 3′ ends of poly(A) RNA cannot be identified unambiguously. This is due in part to RN...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906549/ https://www.ncbi.nlm.nih.gov/pubmed/34728536 http://dx.doi.org/10.1261/rna.078703.121 |