Differential expression of inhibitory receptor NKG2A distinguishes disease‐specific exhausted CD8(+) T cells

Exhausted CD8(+) T (Tex) cells are caused by persistent antigenic stimulation during chronic viral infection or tumorigenesis. Tex cells upregulate and sustain the expressions of multiple immune inhibitory receptors (IRs). Blocking IRs of Tex cells, exemplified by PD‐1, can partially restore their e...

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Detalles Bibliográficos
Autores principales: Chen, Xiangyu, Lin, Yao, Yue, Shuai, Yang, Yang, Wang, Xinxin, Pan, Zhiwei, Yang, Xiaofan, Gao, Leiqiong, Zhou, Jing, Li, Zhirong, Hu, Li, Tang, Jianfang, Wu, Qing, Wang, Yifei, Tian, Qin, Hao, Yaxing, Xu, Lifan, Zhu, Bo, Huang, Qizhao, Ye, Lilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906559/
https://www.ncbi.nlm.nih.gov/pubmed/35281793
http://dx.doi.org/10.1002/mco2.111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906559/
https://www.ncbi.nlm.nih.gov/pubmed/35281793
http://dx.doi.org/10.1002/mco2.111

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