IQCELL: A platform for predicting the effect of gene perturbations on developmental trajectories using single-cell RNA-seq data

The increasing availability of single-cell RNA-sequencing (scRNA-seq) data from various developmental systems provides the opportunity to infer gene regulatory networks (GRNs) directly from data. Herein we describe IQCELL, a platform to infer, simulate, and study executable logical GRNs directly fro...

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Detalles Bibliográficos
Autores principales: Heydari, Tiam, A. Langley, Matthew, Fisher, Cynthia L., Aguilar-Hidalgo, Daniel, Shukla, Shreya, Yachie-Kinoshita, Ayako, Hughes, Michael, M. McNagny, Kelly, Zandstra, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906617/
https://www.ncbi.nlm.nih.gov/pubmed/35213533
http://dx.doi.org/10.1371/journal.pcbi.1009907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906617/
https://www.ncbi.nlm.nih.gov/pubmed/35213533
http://dx.doi.org/10.1371/journal.pcbi.1009907

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