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IQCELL: A platform for predicting the effect of gene perturbations on developmental trajectories using single-cell RNA-seq data
The increasing availability of single-cell RNA-sequencing (scRNA-seq) data from various developmental systems provides the opportunity to infer gene regulatory networks (GRNs) directly from data. Herein we describe IQCELL, a platform to infer, simulate, and study executable logical GRNs directly fro...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906617/ https://www.ncbi.nlm.nih.gov/pubmed/35213533 http://dx.doi.org/10.1371/journal.pcbi.1009907 |