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Cationic Carbosilane Dendrimers Prevent Abnormal α-Synuclein Accumulation in Parkinson’s Disease Patient-Specific Dopamine Neurons

[Image: see text] Accumulation of misfolded α-synuclein (α-syn) is a hallmark of Parkinson’s disease (PD) thought to play important roles in the pathophysiology of the disease. Dendritic systems, able to modulate the folding of proteins, have emerged as promising new therapeutic strategies for PD tr...

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Detalles Bibliográficos
Autores principales: Ferrer-Lorente, Raquel, Lozano-Cruz, Tania, Fernández-Carasa, Irene, Miłowska, Katarzyna, de la Mata, Francisco Javier, Bryszewska, Maria, Consiglio, Antonella, Ortega, Paula, Gómez, Rafael, Raya, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906628/
https://www.ncbi.nlm.nih.gov/pubmed/34613701
http://dx.doi.org/10.1021/acs.biomac.1c00884