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Podocyte VEGF-A Knockdown Induces Diffuse Glomerulosclerosis in Diabetic and in eNOS Knockout Mice

Vascular endothelial growth factor-a (VEGF-A) and nitric oxide (NO) are essential for glomerular filtration barrier homeostasis, and are dysregulated in diabetic kidney disease (DKD). While NO availability is consistently low in diabetes, both high and low VEGF-A have been reported in patients with...

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Detalles Bibliográficos
Autores principales: Veron, Delma, Aggarwal, Pardeep K., Li, Qi, Moeckel, Gilbert, Kashgarian, Michael, Tufro, Alda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906751/
https://www.ncbi.nlm.nih.gov/pubmed/35280251
http://dx.doi.org/10.3389/fphar.2021.788886