Cargando…
Podocyte VEGF-A Knockdown Induces Diffuse Glomerulosclerosis in Diabetic and in eNOS Knockout Mice
Vascular endothelial growth factor-a (VEGF-A) and nitric oxide (NO) are essential for glomerular filtration barrier homeostasis, and are dysregulated in diabetic kidney disease (DKD). While NO availability is consistently low in diabetes, both high and low VEGF-A have been reported in patients with...
Autores principales: | Veron, Delma, Aggarwal, Pardeep K., Li, Qi, Moeckel, Gilbert, Kashgarian, Michael, Tufro, Alda |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906751/ https://www.ncbi.nlm.nih.gov/pubmed/35280251 http://dx.doi.org/10.3389/fphar.2021.788886 |
Ejemplares similares
-
Acute Podocyte Vascular Endothelial Growth Factor (VEGF-A) Knockdown Disrupts alpha(V)beta(3) Integrin Signaling in the Glomerulus
por: Veron, Delma, et al.
Publicado: (2012) -
Semaphorin3a Promotes Advanced Diabetic Nephropathy
por: Aggarwal, Pardeep K., et al.
Publicado: (2015) -
Loss of the podocyte glucocorticoid receptor exacerbates proteinuria after injury
por: Zhou, Han, et al.
Publicado: (2017) -
S-Nitrosylation of RhoGAP Myosin9A Is Altered in Advanced Diabetic Kidney Disease
por: Li, Qi, et al.
Publicado: (2021) -
Cholesterol Accumulation in Podocytes: A Potential Novel Targetable Pathway in Diabetic Nephropathy
por: Tufro, Alda
Publicado: (2013)