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Frequency- and spike-timing-dependent mitochondrial Ca(2+) signaling regulates the metabolic rate and synaptic efficacy in cortical neurons
Mitochondrial activity is crucial for the plasticity of central synapses, but how the firing pattern of pre- and postsynaptic neurons affects the mitochondria remains elusive. We recorded changes in the fluorescence of cytosolic and mitochondrial Ca(2+) indicators in cell bodies, axons, and dendrite...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906805/ https://www.ncbi.nlm.nih.gov/pubmed/35192454 http://dx.doi.org/10.7554/eLife.74606 |