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Elevated TNF-α Induces Thrombophagocytosis by Mononuclear Cells in ex vivo Whole-Blood Co-Culture with Dengue Virus

BACKGROUND: Infection with dengue virus (DENV) causes hematological complications in dengue diseases characterized by thrombocytopenia accompanied by macrophage activation syndrome and hemophagocytosis in fatal patients. METHODS: In this study, we investigate the undefined mechanisms underlying the...

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Detalles Bibliográficos
Autores principales: Satria, Rahmat Dani, Jhan, Ming-Kai, Chen, Chia-Ling, Tseng, Po-Chun, Wang, Yung-Ting, Lin, Chiou-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906901/
https://www.ncbi.nlm.nih.gov/pubmed/35282270
http://dx.doi.org/10.2147/JIR.S356742