ACE2 overexpressing mesenchymal stem cells alleviates COVID-19 lung injury by inhibiting pyroptosis

Mesenchymal stem cells (MSCs) have shown some efficacy in the COVID-19 treatment. We proposed that exogenous supplementation of ACE2 via MSCs (ACE2-MSCs) might have better therapeutic effects. We constructed SARS-CoV-2 spike glycoprotein stably transfected AT-II and Beas-2B cells and used SARS-CoV-2...

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Detalles Bibliográficos
Autores principales: Wei, Jinhuan, Shang, Rui, Wang, Jiaqi, Zhu, Shengze, Yin, JianQiang, Chen, Ying, Zhao, Yayu, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907105/
https://www.ncbi.nlm.nih.gov/pubmed/35287354
http://dx.doi.org/10.1016/j.isci.2022.104046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907105/
https://www.ncbi.nlm.nih.gov/pubmed/35287354
http://dx.doi.org/10.1016/j.isci.2022.104046

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