Cargando…

ACE2 overexpressing mesenchymal stem cells alleviates COVID-19 lung injury by inhibiting pyroptosis

Mesenchymal stem cells (MSCs) have shown some efficacy in the COVID-19 treatment. We proposed that exogenous supplementation of ACE2 via MSCs (ACE2-MSCs) might have better therapeutic effects. We constructed SARS-CoV-2 spike glycoprotein stably transfected AT-II and Beas-2B cells and used SARS-CoV-2...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wei, Jinhuan, Shang, Rui, Wang, Jiaqi, Zhu, Shengze, Yin, JianQiang, Chen, Ying, Zhao, Yayu, Chen, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907105/ https://www.ncbi.nlm.nih.gov/pubmed/35287354 http://dx.doi.org/10.1016/j.isci.2022.104046

Ejemplares similares

Maresin 1 promotes nerve regeneration and alleviates neuropathic pain after nerve injury
por: Wei, Jinhuan, et al.
Publicado: (2022)

Overexpression of aquaporin 2 in renal tubular epithelial cells alleviates pyroptosis
por: Fan, Yu, et al.
Publicado: (2021)

Mesenchymal Stem Cells Overexpressing ACE2 Favorably Ameliorate LPS-Induced Inflammatory Injury in Mammary Epithelial Cells
por: Yan, Shuping, et al.
Publicado: (2022)

Mesenchymal Stem Cells Alleviate Post-resuscitation Cardiac and Cerebral Injuries by Inhibiting Cell Pyroptosis and Ferroptosis in a Swine Model of Cardiac Arrest
por: Xu, Jiefeng, et al.
Publicado: (2021)

Ligustrazine Alleviate Acute Lung Injury Through Suppressing Pyroptosis and Apoptosis of Alveolar Macrophages
por: Jiang, Rundong, et al.
Publicado: (2021)

Human umbilical cord mesenchymal stem cell exosomes alleviate acute kidney injury by inhibiting pyroptosis in rats and NRK-52E cells
por: Wan, Yonghong, et al.
Publicado: (2023)

Chinese Herbal Medicine Suyin Detoxification Granule Inhibits Pyroptosis and Epithelial-Mesenchymal Transition by Downregulating MAVS/NLRP3 to Alleviate Renal Injury
por: Zhu, Yiye, et al.
Publicado: (2021)

Mesenchymal Stem Cells Attenuate Radiation-Induced Brain Injury by Inhibiting Microglia Pyroptosis
por: Liao, Huan, et al.
Publicado: (2017)

Aquaporin 4 inhibition alleviates myocardial ischemia-reperfusion injury by restraining cardiomyocyte pyroptosis
por: Jiang, Qiong, et al.
Publicado: (2021)

Corrigendum to “Mesenchymal Stem Cells Attenuate Radiation-Induced Brain Injury by Inhibiting Microglia Pyroptosis”
por: Liao, Huan, et al.
Publicado: (2018)

Direct Inhibition of GSDMD by PEITC Reduces Hepatocyte Pyroptosis and Alleviates Acute Liver Injury in Mice
por: Wang, Jie, et al.
Publicado: (2022)

Hypoxic preconditioned mesenchymal stem cells ameliorate rat brain injury after cardiopulmonary resuscitation by suppressing neuronal pyroptosis
por: Tang, Xiahong, et al.
Publicado: (2023)

Icariin alleviates osteoarthritis by inhibiting NLRP3-mediated pyroptosis
por: Zu, Yan, et al.
Publicado: (2019)

Mesenchymal stem cells overexpressing hepatocyte nuclear factor-4 alpha alleviate liver injury by modulating anti-inflammatory functions in mice
por: Ye, Zhenxiong, et al.
Publicado: (2019)

Melatonin alleviates lipopolysaccharide-induced myocardial injury by inhibiting inflammation and pyroptosis in cardiomyocytes
por: Su, Ze-Da-Zhong, et al.
Publicado: (2021)

Emodin alleviates myocardial ischemia/reperfusion injury by inhibiting gasdermin D-mediated pyroptosis in cardiomyocytes
por: Ye, Bozhi, et al.
Publicado: (2019)

Emodin alleviates lung ischemia–reperfusion injury by suppressing gasdermin D‐mediated pyroptosis in rats
por: Jin, Tao, et al.
Publicado: (2023)

Exosomes derived from adipose-derived stem cells alleviate cigarette smoke-induced lung inflammation and injury by inhibiting alveolar macrophages pyroptosis
por: Zhu, Zhixing, et al.
Publicado: (2022)

Pyroptosis in spinal cord injury
por: Yin, Jian, et al.
Publicado: (2022)

Intercellular mitochondrial transfer alleviates pyroptosis in dental pulp damage
por: Wang, Konghuai, et al.
Publicado: (2023)

Chitosan Hydrogel Enhances the Therapeutic Efficacy of Bone Marrow–Derived Mesenchymal Stem Cells for Myocardial Infarction by Alleviating Vascular Endothelial Cell Pyroptosis
por: Liu, Yang, et al.
Publicado: (2020)

Exosomal miR-23b from bone marrow mesenchymal stem cells alleviates oxidative stress and pyroptosis after intracerebral hemorrhage
por: Hu, Liu-Ting, et al.
Publicado: (2022)

Methane alleviates sepsis-induced injury by inhibiting pyroptosis and apoptosis: in vivo and in vitro experiments
por: Li, Zeyu, et al.
Publicado: (2019)

Paeonol regulates NLRP3 inflammasomes and pyroptosis to alleviate spinal cord injury of rat
por: Zhao, Houling, et al.
Publicado: (2022)

Castanopsis sieboldii Extract Alleviates Acute Liver Injury by Antagonizing Inflammasome-Mediated Pyroptosis
por: Kim, Jae Min, et al.
Publicado: (2023)

Maresin1 alleviates liver ischemia/reperfusion injury by reducing liver macrophage pyroptosis
por: Li, Tong, et al.
Publicado: (2023)

Inhibition of microRNA-122 alleviates pyroptosis by targeting dual-specificity phosphatase 4 in myocardial ischemia/reperfusion injury
por: Wu, Hongjin, et al.
Publicado: (2023)

Breviscapine alleviates podocyte injury by inhibiting NF-κB/NLRP3-mediated pyroptosis in diabetic nephropathy
por: Sun, Linlin, et al.
Publicado: (2023)

Monotropein attenuates apoptosis and pyroptosis in chondrocytes and alleviates osteoarthritis progression in mice
por: Li, Zhen, et al.
Publicado: (2023)

Stem Cells From Human Exfoliated Deciduous Teeth Alleviate Liver Cirrhosis via Inhibition of Gasdermin D-Executed Hepatocyte Pyroptosis
por: Chen, Peng, et al.
Publicado: (2022)

Mesenchymal stem cell therapy alleviates the neuroinflammation associated with acquired brain injury
por: Bonsack, Brooke, et al.
Publicado: (2020)

HGF alleviates septic endothelial injury by inhibiting pyroptosis via the mTOR signalling pathway
por: Peng, Fei, et al.
Publicado: (2020)

Exosomes Derived from Mesenchymal Stem Cells Protect the Myocardium Against Ischemia/Reperfusion Injury Through Inhibiting Pyroptosis
por: Tang, Jiayou, et al.
Publicado: (2020)

Mesenchymal stem cells alleviate LPS-induced acute lung injury by inhibiting the proinflammatory function of Ly6C(+) CD8(+) T cells
por: Zhu, Jiaqi, et al.
Publicado: (2020)

Mesenchymal Stem Cells Alleviate Bacteria-Induced Liver Injury in Mice by Inducing Regulatory Dendritic Cells
por: Zhang, Yi, et al.
Publicado: (2014)

A Novel Modulator of the Renin–Angiotensin System, Benzoylaconitine, Attenuates Hypertension by Targeting ACE/ACE2 in Enhancing Vasodilation and Alleviating Vascular Inflammation
por: Zhang, Qi-Qiang, et al.
Publicado: (2022)

Mesenchymal stem cells overexpressing PEDF decrease the angiogenesis of gliomas
por: Wang, Qiaoshu, et al.
Publicado: (2013)

Hypoxia-preconditioned mesenchymal stem cells attenuate microglial pyroptosis after intracerebral hemorrhage
por: Liu, Jianyang, et al.
Publicado: (2021)

Bone marrow mesenchymal stem cellsderived exosomes stabilize atherosclerosis through inhibiting pyroptosis
por: Bai, Zhibin, et al.
Publicado: (2023)

HSF1 Alleviates Brain Injury by Inhibiting NLRP3-Induced Pyroptosis in a Sepsis Model
por: He, Yi-fu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_hk342cbobsq4sc1o13mb1pd0p3