Simultaneous mass spectrometry analysis of cisplatin with oligonucleotide-peptide mixtures: implications for the mechanism of action

Although genomic DNA is the primary target of anticancer platinum-based drugs, interactions with proteins also play a significant role in their overall activity. In this study, competitive binding of cisplatin with an oligonucleotide and two peptides corresponding to segments of H2A and H2B histone...

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Detalles Bibliográficos
Autores principales: Mansouri, Farangis, Patiny, Luc, Ortiz, Daniel, Menin, Laure, Davey, Curtis A., Mohammadi, Fakhrossadat, Dyson, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907109/
https://www.ncbi.nlm.nih.gov/pubmed/35064831
http://dx.doi.org/10.1007/s00775-022-01924-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907109/
https://www.ncbi.nlm.nih.gov/pubmed/35064831
http://dx.doi.org/10.1007/s00775-022-01924-9

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