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Beyond the Motor Cortex: Thalamic Iron Deposition Accounts for Disease Severity in Amyotrophic Lateral Sclerosis

OBJECTIVE: Previous studies have reliably identified iron deposition in the motor cortex as potential pathogenesis of amyotrophic lateral sclerosis (ALS). Here, we intended to investigate iron deposition, gray matter (GM) atrophy, and their associations with disease severity in the motor cortex and...

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Detalles Bibliográficos
Autores principales: Li, Qianwen, Zhu, Wenjia, Wen, Xinmei, Zang, Zhenxiang, Da, Yuwei, Lu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907117/
https://www.ncbi.nlm.nih.gov/pubmed/35280261
http://dx.doi.org/10.3389/fneur.2022.791300