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Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1

Within the last 2 decades, severe acute respiratory syndrome coronaviruses 1 and 2 (SARS-CoV-1 and SARS-CoV-2) have caused two major outbreaks; yet, for reasons not fully understood, the coronavirus disease 2019 pandemic caused by SARS-CoV-2 has been significantly more widespread than the 2003 SARS...

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Detalles Bibliográficos
Autores principales: Govind Kumar, Vivek, Ogden, Dylan S., Isu, Ugochi H., Polasa, Adithya, Losey, James, Moradi, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907130/
https://www.ncbi.nlm.nih.gov/pubmed/35278433
http://dx.doi.org/10.1016/j.jbc.2022.101814