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Sex-Specific Cell Types and Molecular Pathways Indicate Fibro-Calcific Aortic Valve Stenosis

BACKGROUND: Aortic stenosis (AS) is the most common valve disorder characterized by fibro-calcific remodeling of leaflets. Recent evidence indicated that there is a sex-related difference in AS development and progression. Fibrotic remodeling is peculiar in women’s aortic valves, while men’s leaflet...

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Detalles Bibliográficos
Autores principales: Myasoedova, Veronika A., Massaiu, Ilaria, Moschetta, Donato, Chiesa, Mattia, Songia, Paola, Valerio, Vincenza, Alfieri, Valentina, Capoulade, Romain, Trabattoni, Daniela, Andreini, Daniele, Mass, Elvira, Parisi, Valentina, Poggio, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907138/
https://www.ncbi.nlm.nih.gov/pubmed/35280999
http://dx.doi.org/10.3389/fimmu.2022.747714