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Intermediate-Intensity Autologous Hematopoietic Stem Cell Transplantation Reduces Serum Neurofilament Light Chains and Brain Atrophy in Aggressive Multiple Sclerosis

BACKGROUND: Autologous haematopoietic stem cell transplantation (AHSCT) is highly effective in reducing new inflammatory activity in aggressive multiple sclerosis (MS). A remarkable decrease of serum neurofilament light chains (sNfL) concentration, a marker of axonal damage, was reported in MS follo...

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Detalles Bibliográficos
Autores principales: Mariottini, Alice, Marchi, Leonardo, Innocenti, Chiara, Di Cristinzi, Maria, Pasca, Matteo, Filippini, Stefano, Barilaro, Alessandro, Mechi, Claudia, Fani, Arianna, Mazzanti, Benedetta, Biagioli, Tiziana, Materozzi, Francesca, Saccardi, Riccardo, Massacesi, Luca, Repice, Anna Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907141/
https://www.ncbi.nlm.nih.gov/pubmed/35280289
http://dx.doi.org/10.3389/fneur.2022.820256