CTLA-4 Facilitates DNA Damage–Induced Apoptosis by Interacting With PP2A

Cytotoxic T-lymphocyte–associated protein 4 (CTLA-4) plays a pivotal role in regulating immune responses. It accumulates in intracellular compartments, translocates to the cell surface, and is rapidly internalized. However, the cytoplasmic function of CTLA-4 remains largely unknown. Here, we describ...

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Detalles Bibliográficos
Autores principales: Yan, Qiongyu, Zhang, Bin, Ling, Xi, Zhu, Bin, Mei, Shenghui, Yang, Hua, Zhang, Dongjie, Huo, Jiping, Zhao, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907142/
https://www.ncbi.nlm.nih.gov/pubmed/35281086
http://dx.doi.org/10.3389/fcell.2022.728771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907142/
https://www.ncbi.nlm.nih.gov/pubmed/35281086
http://dx.doi.org/10.3389/fcell.2022.728771

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