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CTLA-4 Facilitates DNA Damage–Induced Apoptosis by Interacting With PP2A
Cytotoxic T-lymphocyte–associated protein 4 (CTLA-4) plays a pivotal role in regulating immune responses. It accumulates in intracellular compartments, translocates to the cell surface, and is rapidly internalized. However, the cytoplasmic function of CTLA-4 remains largely unknown. Here, we describ...
Autores principales: | Yan, Qiongyu, Zhang, Bin, Ling, Xi, Zhu, Bin, Mei, Shenghui, Yang, Hua, Zhang, Dongjie, Huo, Jiping, Zhao, Zhigang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907142/ https://www.ncbi.nlm.nih.gov/pubmed/35281086 http://dx.doi.org/10.3389/fcell.2022.728771 |
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