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Conformation-specific Antibodies Targeting Aggregated Forms of α-synuclein Block the Propagation of Synucleinopathy

Abnormal aggregation of α-synuclein is a key element in the pathogenesis of several neurodegenerative diseases, including Parkinson’s disease (PD), dementia with Lewy bodies, and multiple system atrophy. α-synuclein aggregation spreads through various brain regions during the course of disease progr...

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Detalles Bibliográficos
Autores principales: Choi, Minsun, Kim, Tae-kyung, Ahn, Jinhyung, Lee, Jun Sung, Jung, Byung Chul, An, Sungwon, Kim, Dongin, Lee, Min Jae, Mook-Jung, Inhee, Lee, Sang Hoon, Lee, Seung-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907253/
https://www.ncbi.nlm.nih.gov/pubmed/35256542
http://dx.doi.org/10.5607/en21039