Cargando…
Restoring nuclear entry of Sirtuin 2 in oligodendrocyte progenitor cells promotes remyelination during ageing
The age-dependent decline in remyelination potential of the central nervous system during ageing is associated with a declined differentiation capacity of oligodendrocyte progenitor cells (OPCs). The molecular players that can enhance OPC differentiation or rejuvenate OPCs are unclear. Here we show...
Autores principales: | Ma, Xiao-Ru, Zhu, Xudong, Xiao, Yujie, Gu, Hui-Min, Zheng, Shuang-Shuang, Li, Liang, Wang, Fan, Dong, Zhao-Jun, Wang, Di-Xian, Wu, Yang, Yang, Chenyu, Jiang, Wenhong, Yao, Ke, Yin, Yue, Zhang, Yang, Peng, Chao, Gao, Lixia, Meng, Zhuoxian, Hu, Zeping, Liu, Chong, Li, Li, Chen, Hou-Zao, Shu, Yousheng, Ju, Zhenyu, Zhao, Jing-Wei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907257/ https://www.ncbi.nlm.nih.gov/pubmed/35264567 http://dx.doi.org/10.1038/s41467-022-28844-1 |
Ejemplares similares
-
Inhibition of RIPK1 by ZJU-37 promotes oligodendrocyte progenitor proliferation and remyelination via NF-κB pathway
por: Ma, Xiao-Ru, et al.
Publicado: (2022) -
Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination
por: De La Fuente, Alerie Guzman, et al.
Publicado: (2017) -
Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors
por: Gautier, Hélène O. B., et al.
Publicado: (2015) -
DCX(+) neuronal progenitors contribute to new oligodendrocytes during remyelination in the hippocampus
por: Klein, Barbara, et al.
Publicado: (2020) -
OCT4-induced oligodendrocyte progenitor cells promote remyelination and ameliorate disease
por: Yun, Wonjin, et al.
Publicado: (2022)