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PET in vivo generators (134)Ce and (140)Nd on an internalizing monoclonal antibody probe
The in vivo-generator radionuclides (140)Nd (t(1/2) = 3.4 d) and (134)Ce (t(1/2) = 3.2 d) were used to trace a urokinase-type plasminogen activator (uPA)-targeting mouse monoclonal antibody, ATN-291, in U87 MG xenograft tumor-bearing mice. ATN-291 is known to internalize on the uPA/uPA-receptor pair...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907281/ https://www.ncbi.nlm.nih.gov/pubmed/35264588 http://dx.doi.org/10.1038/s41598-022-07147-x |