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Effect of morpholine and charge distribution of cyanine dyes on cell internalization and cytotoxicity

To improve the potency of Heptamethine cyanines (Hcyanines) in cancer research, we designed and synthesized two novel Hcyanines based theranostic probes, IR794-Morph and IR794-Morph-Mpip, to enhance cancer cell internalization and targeting. In acidic conditions that resemble to tumour environment,...

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Detalles Bibliográficos
Autores principales: Wangngae, Sirilak, Chansaenpak, Kantapat, Weeranantanapan, Oratai, Piyanuch, Pornthip, Sumphanapai, Thitima, Yamabhai, Montarop, Noisa, Parinya, Lai, Rung-Yi, Kamkaew, Anyanee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907291/
https://www.ncbi.nlm.nih.gov/pubmed/35264603
http://dx.doi.org/10.1038/s41598-022-07533-5