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Effect of morpholine and charge distribution of cyanine dyes on cell internalization and cytotoxicity
To improve the potency of Heptamethine cyanines (Hcyanines) in cancer research, we designed and synthesized two novel Hcyanines based theranostic probes, IR794-Morph and IR794-Morph-Mpip, to enhance cancer cell internalization and targeting. In acidic conditions that resemble to tumour environment,...
Autores principales: | Wangngae, Sirilak, Chansaenpak, Kantapat, Weeranantanapan, Oratai, Piyanuch, Pornthip, Sumphanapai, Thitima, Yamabhai, Montarop, Noisa, Parinya, Lai, Rung-Yi, Kamkaew, Anyanee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907291/ https://www.ncbi.nlm.nih.gov/pubmed/35264603 http://dx.doi.org/10.1038/s41598-022-07533-5 |
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