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Quantitative proteomic analysis of the lysine acetylome reveals diverse SIRT2 substrates

Sirtuin 2 (SIRT2) is a NAD+-dependent deacetylase, which regulates multiple biological processes, including genome maintenance, aging, tumor suppression, and metabolism. While a number of substrates involved in these processes have been identified, the global landscape of the SIRT2 acetylome remains...

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Detalles Bibliográficos
Autores principales: Zhang, Hui, Dammer, Eric B., Duong, Duc M., Danelia, Diana, Seyfried, Nicholas T., Yu, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907344/
https://www.ncbi.nlm.nih.gov/pubmed/35264593
http://dx.doi.org/10.1038/s41598-022-06793-5