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Quantitative proteomic analysis of the lysine acetylome reveals diverse SIRT2 substrates
Sirtuin 2 (SIRT2) is a NAD+-dependent deacetylase, which regulates multiple biological processes, including genome maintenance, aging, tumor suppression, and metabolism. While a number of substrates involved in these processes have been identified, the global landscape of the SIRT2 acetylome remains...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907344/ https://www.ncbi.nlm.nih.gov/pubmed/35264593 http://dx.doi.org/10.1038/s41598-022-06793-5 |