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Pleiotropic actions of phenothiazine drugs are detrimental to Gram-negative bacterial persister cells

Bacterial persister cells are temporarily tolerant to bactericidal antibiotics but are not necessarily dormant and may exhibit physiological activities leading to cell damage. Based on the link between fluoroquinolone-mediated SOS responses and persister cell recovery, we screened chemicals that tar...

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Detalles Bibliográficos
Autores principales: Mohiuddin, Sayed Golam, Nguyen, Thao Vy, Orman, Mehmet A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907348/
https://www.ncbi.nlm.nih.gov/pubmed/35264714
http://dx.doi.org/10.1038/s42003-022-03172-8