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First-in-human immunoPET imaging of HIV-1 infection using (89)Zr-labeled VRC01 broadly neutralizing antibody

A major obstacle to achieving long-term antiretroviral (ART) free remission or functional cure of HIV infection is the presence of persistently infected cells that establish a long-lived viral reservoir. HIV largely resides in anatomical regions that are inaccessible to routine sampling, however, an...

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Detalles Bibliográficos
Autores principales: Beckford-Vera, Denis R., Flavell, Robert R., Seo, Youngho, Martinez-Ortiz, Enrique, Aslam, Maya, Thanh, Cassandra, Fehrman, Emily, Pardons, Marion, Kumar, Shreya, Deitchman, Amelia N., Ravanfar, Vahid, Schulte, Brailee, Wu, I-Wei Katherine, Pan, Tony, Reeves, Jacqueline D., Nixon, Christopher C., Iyer, Nikita S., Torres, Leonel, Munter, Sadie E., Hyunh, Tony, Petropoulos, Christos J., Hoh, Rebecca, Franc, Benjamin L., Gama, Lucio, Koup, Richard A., Mascola, John R., Chomont, Nicolas, Deeks, Steven G., VanBrocklin, Henry F., Henrich, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907355/
https://www.ncbi.nlm.nih.gov/pubmed/35264559
http://dx.doi.org/10.1038/s41467-022-28727-5