Pulmonary fibrosis model using micro-CT analyzable human PSC–derived alveolar organoids containing alveolar macrophage-like cells

Human lung organoids (hLOs) are useful for disease modelling and drug screening. However, a lack of immune cells in hLOs limits the recapitulation of in vivo cellular physiology. Here, we generated hLOs containing alveolar macrophage (AMφ)–like cells derived from pluripotent stem cells (PSC). To bri...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Seri, Choi, Jiwoong, Cheon, Seongmin, Song, Jihong, Kim, Seung-Yeon, Kim, Ji-eun, Nam, Dae-Hwan, Manzar, Gohar, Kim, Su-Man, Kang, Hyung-Sik, Kim, Kee K., Jeong, Sang Hoon, Lee, Ju-Han, Park, Eun-Kee, Lee, Minseob, Lee, Hyang-Ae, Kim, Ki-Suk, Park, Han-Jin, Oh, Won Keun, Park, Chungoo, Lee, Chang Hyun, Kim, Eun-Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907399/
https://www.ncbi.nlm.nih.gov/pubmed/35267148
http://dx.doi.org/10.1007/s10565-022-09698-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907399/
https://www.ncbi.nlm.nih.gov/pubmed/35267148
http://dx.doi.org/10.1007/s10565-022-09698-1

Ejemplares similares