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Estradiol Ameliorates Acute Kidney Ischemia-Reperfusion Injury by Inhibiting the TGF-βRI-SMAD Pathway

Renal ischemia–reperfusion injury (IRI) is less extensive in females than males in both animals and humans; however, this protection diminishes after menopause, suggesting that estrogen plays a pivotal role in IRI, but the underlying mechanism remains largely unknown. Our study found that 45 min of...

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Detalles Bibliográficos
Autores principales: Ren, Lian, Li, Fang, Di, Ziyang, Xiong, Yan, Zhang, Shichen, Ma, Qing, Bian, Xiaoen, Lang, Zhiquan, Ye, Qifa, Wang, Yanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907449/
https://www.ncbi.nlm.nih.gov/pubmed/35281024
http://dx.doi.org/10.3389/fimmu.2022.822604