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Inhibition of IL17A Using an Affibody Molecule Attenuates Inflammation in ApoE-Deficient Mice

The balance between pro- and anti-inflammatory cytokines released by immune and non-immune cells plays a decisive role in the progression of atherosclerosis. Interleukin (IL)-17A has been shown to accelerate atherosclerosis. In this study, we investigated the effect on pro-inflammatory mediators and...

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Detalles Bibliográficos
Autores principales: Kumawat, Ashok Kumar, Zegeye, Mulugeta M., Paramel, Geena Varghese, Baumgartner, Roland, Gisterå, Anton, Amegavie, Obed, Hellberg, Sanna, Jin, Hong, Caravaca, April S., Söderström, Leif Å., Gudmundsdotter, Lindvi, Frejd, Fredrik Y., Ljungberg, Liza U., Olofsson, Peder S., Ketelhuth, Daniel F. J., Sirsjö, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907570/
https://www.ncbi.nlm.nih.gov/pubmed/35282365
http://dx.doi.org/10.3389/fcvm.2022.831039