Gasdermin-B Pro-Tumor Function in Novel Knock-in Mouse Models Depends on the in vivo Biological Context

Gasdermins (GSDM) genes play complex roles in inflammatory diseases and cancer. Gasdermin-B (GSDMB) is frequently upregulated in human cancers, especially in HER2-amplified breast carcinomas, and can promote diverse pro-tumor functions (invasion, metastasis, therapy-resistance). In particular, the G...

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Detalles Bibliográficos
Autores principales: Sarrio, David, Rojo-Sebastián, Alejandro, Teijo, Ana, Pérez-López, María, Díaz-Martín, Eva, Martínez, Lidia, Morales, Saleta, García-Sanz, Pablo, Palacios, José, Moreno-Bueno, Gema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907722/
https://www.ncbi.nlm.nih.gov/pubmed/35281099
http://dx.doi.org/10.3389/fcell.2022.813929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907722/
https://www.ncbi.nlm.nih.gov/pubmed/35281099
http://dx.doi.org/10.3389/fcell.2022.813929

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