Crystallization of Feline Coronavirus M(pro) With GC376 Reveals Mechanism of Inhibition

Coronaviruses infect a variety of hosts in the animal kingdom, and while each virus is taxonomically different, they all infect their host via the same mechanism. The coronavirus main protease (M(pro), also called 3CL(pro)), is an attractive target for drug development due to its essential role in m...

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Detalles Bibliográficos
Autores principales: Lu, Jimmy, Chen, Sizhu Amelia, Khan, Muhammad Bashir, Brassard, Raelynn, Arutyunova, Elena, Lamer, Tess, Vuong, Wayne, Fischer, Conrad, Young, Howard S., Vederas, John C., Lemieux, M. Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907848/
https://www.ncbi.nlm.nih.gov/pubmed/35281564
http://dx.doi.org/10.3389/fchem.2022.852210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907848/
https://www.ncbi.nlm.nih.gov/pubmed/35281564
http://dx.doi.org/10.3389/fchem.2022.852210

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