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Epigenetic Modifier Supplementation Improves Mitochondrial Respiration and Growth Rates and Alters DNA Methylation of Bovine Embryonic Fibroblast Cells Cultured in Divergent Energy Supply

Epigenetic modifiers (EM; methionine, choline, folate, and vitamin B(12)) are important for early embryonic development due to their roles as methyl donors or cofactors in methylation reactions. Additionally, they are essential for the synthesis of nucleotides, polyamines, redox equivalents, and ene...

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Detalles Bibliográficos
Autores principales: Crouse, Matthew S., Caton, Joel S., Claycombe-Larson, Kate J., Diniz, Wellison J. S., Lindholm-Perry, Amanda K., Reynolds, Lawrence P., Dahlen, Carl R., Borowicz, Pawel P., Ward, Alison K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907857/
https://www.ncbi.nlm.nih.gov/pubmed/35281844
http://dx.doi.org/10.3389/fgene.2022.812764