Dapagliflozin Reduces Apoptosis of Diabetic Retina and Human Retinal Microvascular Endothelial Cells Through ERK1/2/cPLA2/AA/ROS Pathway Independent of Hypoglycemic

Introduction: It is known that the metabolic disorder caused by high glucose is one of pathogenesis in diabetic retinopathy (DR), the leading cause of blindness, due to the main pathological change of apoptosis of endothelial cells (ECs). In previous studies, the potential impact of sodium glucose c...

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Detalles Bibliográficos
Autores principales: Hu, Yuxin, Xu, Qian, Li, Hongxue, Meng, Ziyu, Hao, Ming, Ma, Xuefei, Lin, Wenjian, Kuang, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908030/
https://www.ncbi.nlm.nih.gov/pubmed/35281932
http://dx.doi.org/10.3389/fphar.2022.827896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908030/
https://www.ncbi.nlm.nih.gov/pubmed/35281932
http://dx.doi.org/10.3389/fphar.2022.827896

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