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A novel TanCAR targeting IL13Rα2 and EphA2 for enhanced glioblastoma therapy

Chimeric antigen receptor T cell (CAR-T) therapy has been shown to be an effective strategy for combatting non-solid tumors; however, CAR-T therapy is still a challenge for solid tumors, such as glioblastoma. To improve CAR-T therapy for glioblastoma, a new TanCAR, comprising the tandem arrangement...

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Detalles Bibliográficos
Autores principales: Muhammad, Niaz, Wang, Rong, Li, Wenyan, Zhang, Zihan, Chang, Yongxing, Hu, Yitao, Zhao, Junli, Zheng, Xiaojing, Mao, Qinwen, Xia, Haibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908045/
https://www.ncbi.nlm.nih.gov/pubmed/35317513
http://dx.doi.org/10.1016/j.omto.2022.02.012