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Anticancer effects of a single intramuscular dose of a minicircle DNA vector expressing anti-CD3/CD20 in a xenograft mouse model

Bispecific antibodies (BsAbs) are a class of promising anticancer immunotherapies. Among them, the US Food and Drug Administration (FDA)-approved blinatumomab (BLI) is very effective in eliminating the minimum residual disease (MRD) of acute lymphoblastic leukemia (ALL), resulting in long-term remis...

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Detalles Bibliográficos
Autores principales: Pang, Xiaojuan, Chen, Guochuang, Huang, Ping, Zhang, Peifa, Liu, Jie, Hou, Xiaohu, He, Cheng-Yi, Chen, Ping, Xie, Yi-Wu, Zhao, Jing, Chen, Zhi-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908050/
https://www.ncbi.nlm.nih.gov/pubmed/35317514
http://dx.doi.org/10.1016/j.omto.2022.02.014