CircRHBDD1 augments metabolic rewiring and restricts immunotherapy efficacy via m(6)A modification in hepatocellular carcinoma

Circular RNAs are a class of highly conserved RNAs with stable covalently closed circular structures. Metabolic reprogramming of cancer cells reshapes the tumor microenvironment and can suppress antitumor immunity. Here, we discovered a novel circular RNA, termed circRHBDD1, which augments aerobic g...

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Detalles Bibliográficos
Autores principales: Cai, Juan, Chen, Zhiqiang, Zhang, Yao, Wang, Jinguo, Zhang, Zhengrong, Wu, Jindao, Mao, Jiading, Zuo, Xueliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908059/
https://www.ncbi.nlm.nih.gov/pubmed/35317519
http://dx.doi.org/10.1016/j.omto.2022.02.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908059/
https://www.ncbi.nlm.nih.gov/pubmed/35317519
http://dx.doi.org/10.1016/j.omto.2022.02.021

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