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CircRHBDD1 augments metabolic rewiring and restricts immunotherapy efficacy via m(6)A modification in hepatocellular carcinoma
Circular RNAs are a class of highly conserved RNAs with stable covalently closed circular structures. Metabolic reprogramming of cancer cells reshapes the tumor microenvironment and can suppress antitumor immunity. Here, we discovered a novel circular RNA, termed circRHBDD1, which augments aerobic g...
Autores principales: | Cai, Juan, Chen, Zhiqiang, Zhang, Yao, Wang, Jinguo, Zhang, Zhengrong, Wu, Jindao, Mao, Jiading, Zuo, Xueliang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908059/ https://www.ncbi.nlm.nih.gov/pubmed/35317519 http://dx.doi.org/10.1016/j.omto.2022.02.021 |
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