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Myostatin is involved in skeletal muscle dysfunction in chronic obstructive pulmonary disease via Drp-1 mediated abnormal mitochondrial division

BACKGROUND: Skeletal muscle dysfunction (SMD) is one of the most prominent extrapulmonary effects of chronic obstructive pulmonary disease (COPD). Myostatin negatively regulates the growth of skeletal muscle. We confirmed that myostatin expression is significantly increased in the quadriceps femoris...

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Detalles Bibliográficos
Autores principales: Tan, Zhidan, Zhao, Manzhi, Li, Jing, Li, Siqi, Zhu, Su, Yao, Xiaoxuan, Gao, Xinglin, Yang, Shifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908114/
https://www.ncbi.nlm.nih.gov/pubmed/35280400
http://dx.doi.org/10.21037/atm-22-377