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Clinical and molecular impacts of tumor mutational burden in histological and cytological specimens from cancer patients
BACKGROUND: The tumor mutational burden (TMB) is a promising biomarker for immune checkpoint inhibitor (ICI). However, its relationships with clinical parameters have not been fully explored. We aimed to assess potential factors including age, microsatellite instability (MSI) state, tumor types, and...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908122/ https://www.ncbi.nlm.nih.gov/pubmed/35280376 http://dx.doi.org/10.21037/atm-22-358 |