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Genomic landscape and prognosis of patients with TP53-mutated non-small cell lung cancer

BACKGROUND: The TP53 tumor suppressor gene plays an important role in preventing and inhibiting the growth of tumor by regulating cell cycle, apoptosis and DNA repair. Meanwhile, the TP53 gene is one of the most frequently altered gene in non-small cell lung cancer (NSCLC) patients. Mutant TP53 (TP5...

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Detalles Bibliográficos
Autores principales: Fan, Zhisong, Zhang, Qi, Feng, Li, Wang, Long, Zhou, Xinliang, Han, Jing, Li, Dan, Liu, Jiayin, Zhang, Xue, Zuo, Jing, Zou, Xiao, Cai, Yiran, Sun, Ying, Wang, Yudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908146/
https://www.ncbi.nlm.nih.gov/pubmed/35280362
http://dx.doi.org/10.21037/atm-22-412