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SENP1 inhibition suppresses the growth of lung cancer cells through activation of A20-mediated ferroptosis
BACKGROUND: Ferroptosis is a type of cell death driven by iron accumulation and lipid peroxidation, which is involved in the pathogenesis of various tumors. Small ubiquitin-like modifier (SUMO)-specific protease 1 (SENP1) is a critical SUMO-specific protease, which controls multiple cellular signali...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908163/ https://www.ncbi.nlm.nih.gov/pubmed/35280420 http://dx.doi.org/10.21037/atm-21-6909 |