SENP1 inhibition suppresses the growth of lung cancer cells through activation of A20-mediated ferroptosis

BACKGROUND: Ferroptosis is a type of cell death driven by iron accumulation and lipid peroxidation, which is involved in the pathogenesis of various tumors. Small ubiquitin-like modifier (SUMO)-specific protease 1 (SENP1) is a critical SUMO-specific protease, which controls multiple cellular signali...

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Detalles Bibliográficos
Autores principales: Gao, Chuancheng, Xiao, Fengjun, Zhang, Lin, Sun, Yang, Wang, Lei, Liu, Xiang, Sun, Huiyan, Xie, Zhidan, Liang, Yaqi, Xu, Qinqin, Wang, Lisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908163/
https://www.ncbi.nlm.nih.gov/pubmed/35280420
http://dx.doi.org/10.21037/atm-21-6909

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