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MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes

MYCT1 has been shown to function as a tumor suppressor in various tumors, but its role in metabolism has never been reported. Here, we showed that global inactivation of Myct1 in mice led to progressive accumulation of glycogen in the liver, which was accompanied by aberrant changes in intermediates...

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Detalles Bibliográficos
Autores principales: Ding, Dong-Xue, Wang, Yue, Yan, Wei, Fu, Wei-Neng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908216/
https://www.ncbi.nlm.nih.gov/pubmed/35281731
http://dx.doi.org/10.1016/j.isci.2022.103955