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In vitro anticancer effects of alpelisib against PIK3CA-mutated canine hemangiosarcoma cell lines

Hemangiosarcoma (HSA) is a malignant neoplasm that occurs in humans and canines with a poor prognosis owing to metastatic spread, despite effective treatment. The frequency of spontaneous HSA development is higher in canines than in humans. Therefore, canine HSA is a useful model of intractable huma...

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Detalles Bibliográficos
Autores principales: Maeda, Marika, Ochiai, Kazuhiko, Michishita, Masaki, Morimatsu, Masami, Sakai, Hiroki, Kinoshita, Nayuta, Sakaue, Motoharu, Onozawa, Eri, Azakami, Daigo, Yamamoto, Masami, Ishioka, Katsumi, Sadahira, Takuya, Watanabe, Masami, Tanaka, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908334/
https://www.ncbi.nlm.nih.gov/pubmed/35234262
http://dx.doi.org/10.3892/or.2022.8295